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GLP-1 agonists like semaglutide help lower blood sugar levels by increasing the amount of insulin released by the pancreas and decreasing the amount of glucose produced by the liver, notes Chris Damman, M.D., clinical associate professor of Gastroenterology and Medicine at the University of Washington and the chief medical officer of supplement company Supergut

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Unlike over-the-counter supplements, these therapies are clinically dosed and delivered directly into the body under medical supervision

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Injections bypass the gut, and for these patients treatment is often a long-term maintenance strategy guided by their provider