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Research from medical journals indicates that topical glutathione can significantly decrease melanin index in sun-exposed areas within weeks

Overexpression of MDH2 under these conditions increases OAA, which can be transaminated to aspartate, while GLU derived -KG is simultaneously diverted to L -2HG formation (94)

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The post-translationally functioning nucleo-cytoplasmic protein for O-GlcNAcylation first appeared in prokaryota, and remained functional in the low-branching Giardia and in the placozoan Trichoplax adhaerens (69), cultured and fed by red alga Rhodomonas salina

Authors also show that COVID-19 mortality was about 1.5x higher when compared with influenza in the first two pandemic waves, but there was no significant difference in the third wave (HR 1.53 [1.45-1.62] and 1.52 [1.44-1.61] in the first two waves and 1.07 [0.99-1.14] in the third)