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What the animal studies cannot tell us includes optimal human dosing, population-specific responses (elderly, children, pregnancy), long-term safety in humans, rare side effects that require large sample sizes to detect, and interactions with medications or medical conditions

Le Martret B, Poage M, Shiel K, Nugent GD, Dix PJ

The percentage that reaches systemic circulation intact is estimated to be quite low, though exact figures for GHK-Cu specifically aren't well established in published literature

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Brain areas involved in the emotional and motivational responses to chronic pain were also impacted by paclitaxel treatment