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Therefore, for SLE and LN treatment, adoptive transfer of Tregs can be directly applied, either as polyclonal Tregs or as engineered variants with a receptor of high affinity for the target autoantigen, such as TCR-Tregs or CAR-Tregs, to eliminate or deactivate aberrant immune cells and reduce inflammation in AIDs (75)

10.3390/molecules26113328 9 HanJ.ZhangL.GuoH.WyshamW

Clinical evidence demonstrates that oral doses of 13 grams per day, administered for 612 months, can reduce neuropathic pain scores, with enhancements in nerve fiber regeneration and sensory function, particularly when combined with standard therapies [5]