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2.3 Gut-kidney interactions The gut-kidney axis is an emerging field of study that highlights the bidirectional communication between these two organs, with the gut microbiota playing a significant role in their function and disease

This imbalance occurs because the body senses too much thyroid hormone in the bloodstream, signaling the pituitary gland to reduce TSH release in an attempt to restore hormonal balance

However, edaravone causes hypersensitivity and allergic reactions in some patients and may be effective in less than 5% of the ALS population [Table 3)