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Chapter 6: Estrogen metabolism by conjugation

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By blocking NNMT , 5-Amino-1MQ: At the enzyme level it binds within NNMTs substrate pocket with high selectivity

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Current research protocols typically employ cycling approaches (4-8 weeks active, 2-6 weeks rest) rather than continuous long-term use

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BIO-65043) and gene expression was determined using RT-qPCR performed with a Roche LightCycler 480 system (Roche Diagnostics Corporation, Indianapolis, Indiana, USA) according to MIQE recommendations 57 as previously described 19

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