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Although its pathogenesis cannot be explained by a single hypothesis, several mechanisms are especially relevant to nanotherapeutic intervention, including neurotransmitter imbalance, hypothalamicpituitaryadrenal (HPA) axis dysregulation, neuroinflammation, oxidative stress, and impaired neuroplasticity (Fig

Unlike some peptides that require cycling to prevent receptor desensitization, AOD-9604 does not appear to lose efficacy with continuous use based on available data

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Clinical translation isnt tested

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