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The immune system is often struggling to keep up during times of heightened stress, either due to lower nutrient intake (e.g., malnutrition, crash-dieting, strict calorie-restrictive diets, excessive intake of ultra-processed and nutrient-poor foodstuff), chronic stress (including anxiety and depression), tobacco smoking, excessive alcohol intake, and infections (e.g., colds and flu)

For example, people who exercise frequently and intensely have the same mortality rates as people who lead a sedentary lifestyle (Van Houten et al., 2015)

8, 2025, Paroli M, Gioia C, Accapezzato D, Caccavale R

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