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Koyuncu H, Fidan V, Toktas H, Binay O, Celik H

Dec 312021Pharmaceutical intermediates Chlorambucil, approved by the Food and Drug Administration (FDA) in 1957, is an antineoplastic/alkylating agent with a broad spectrum of antitumor activity used to treat chronic lymphocytic leukemia (CLL), Hodgkins and non-Hodgkins lympho

Negative Control animals received identical procedures except for the application of the PEG solution

Due to the limited availability of early diagnostic techniques and the prevalence of chemotherapy resistance, the overall survival rate for individuals with advanced OC remains considerably low

The findings indicate that cerebral I/R injury not only causes a specific type of programmed neuronal death called PANoptosis but also triggers microglia to adopt a pro-inflammatory (M1) phenotype, both in living organisms and in vitro