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In particular, increased Gram-negative bacteria expose KCs to an elevated amount of LPS and upregulation of PRRs ( Also, the association between obstructive sleep apnea syndrome (OSAS) and NASH severity seems to correlate with endotoxemia increase and gut barrier function alteration, conducing to increased hepatic susceptibility to endotoxemia mediated by TLR-4 (98)

Immunofluorescence-stained slides were imaged using a Zeiss Axioimager.M2m with an AxioCam MRm camera and the AxioVision program for imaging

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