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Glutathione works in the body by facilitating Phase II detoxification for excretion of xenobiotic and endogenous compounds

10.1016/j.freeradbiomed.2009.06.001 152 XuZ.AdilijiangA.WangW.YouP.LinD.LiX.et al (2019)

Aging is associated with reduced mitophagy and lysosomal degradation, along with increased ER folding stress, which affects signaling at membrane contact sites, resulting in sustained proteostasis imbalance

The concept of hypoxia as an insufficient supply of oxygen to tissues and cells was initially associated only with pathological conditions (Meerson, 1984)

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