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Administration of COMT inhibitors effectively reduces Hcy but obtained data of several studies that focused on inhibitors effect on levodopa-induced HHcy are ambiguous [120, 127]

Fighting Oxidative Stress with Glutathione Oxidative stress is a major factor contributing to poor gut health

The protective effect of glutamine was detectable for 72 hours after IRI induction, which represents the latest time point to be assessed before mice started dying (Figure 1F)

Peripheral supplementation of MANF has shown potential to reduce infarct volume and neuroinflammation in ischemic stroke models, highlighting its therapeutic promise for other neurological diseases [149]