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[3] [6] The medication also acts on areas of the brain involved in appetite regulation

Inflammation and its resolution in human health: implications for tissue repair

That's a choice, and something I've done in the past with certain translations

2021;137(6):e128-e144

The integrity of the endothelium and oxidative damage could be restored and reversed respectively, which was linked to the increased expression and internalisation of VEGFR2