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Thorax (2018) 73(5):43945

Sample preparation and analysis were carried out as described previously at Metabolon 59

In Method 1 the bulk of the more rapidly sedimenting PC may then separated from the NPC by repeated differential pelleting at 50 g for 1-4 min

The variation in EE were attributed to differences in the carrier composition and surfactant concentration, which influence drug portioning and entrapment within the lipid matrix 36,37