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As illustrated in Figure 4, the gut microbiota serves as a central hub in diabetic lung injury, where gut-derived metabolites and toxins (e.g., LPS, BCAAs) remotely regulate pulmonary inflammation and immune responses through systemic circulation, ultimately leading to endothelial disruption and oxidative stress

MicroRNA-193a-3p Participates in the Progression of Rheumatoid Arthritis by Regulating Proliferation and Apoptosis of MH7A Cells Through Targeting IGFBP5

Lefkovits, 1997)

The incidence of ASD typically ranges from 2% to 36%, depending on the specific spinal region involved (such as the lumbar or cervical spine) and the duration of follow-up (Huang et al., 2025)

4a), whereas the communication strength of adipocytes with other AT-resident cell types, like endothelial cells, remained unchanged