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However, long-term mucolytics exposure is associated with inflammation, metabolic syndrome and increased microbial proximity 205

The stronger structural distortion seen in our MD simulation as compared to our CD results could thus be contributed by multiple factors

These products are formed through the interaction of ROS with lipids, leading to cell membrane damage, protein modification, and DNA injury, thereby accelerating disease progression [129]

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Stockwell and others officially introduced the concept of ferroptosis to describe the iron-dependent cell death driven by lipid peroxidation on the plasma membranes of cells ( Ferroptosis differs from other forms of cell death, such as apoptosis, necroptosis, pyroptosis, and autophagy