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In addition to functioning as a reversible electron carrier, it participates directly in the catalytic activity of multiple NAD+-dependent enzyme families

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As shown in Fig.32, according to material balance law, along the section, the equation below is founded: In which can be calculated by each C of all the sections, can be calculated by the height of filter through each section and the filter velocity

The authors compared the metabolic profile to the diabetes drug metformin, but stopped short of saying the two are interchangeable