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Zebda R, Paller AS (2018) Phosphodiesterase 4 inhibitors

This action is possible due to their capacity to inhibit pathways that trigger oxidative stress, and the synthesis and release of cytokines and chemokines, which are proinflammatory chemicals

Selank is a tuftsin analog that modulates GABA-A receptor sensitivity (without directly being a GABA agonist), inhibits enkephalin breakdown, and has anxiolytic effects