genital melanotic macules pictures macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Mystery behind labial and oral

Although the exact link between Erastin and pyroptosis remains unclear, Erastin-induced ferroptosis generates a substantial amount of ROS

A randomized phase I/II trial of 30 HCC patients investigated autologous dendritic cell tumor injection versus RFA combined with OK432-stimulated DC tumor injection (99)

The combination is appealing because using a GHRH analogue such as CJC-1295 with a secretagogue like Ipamorelin potentially allows lower frequency dosing, better control over GH peaks/troughs, and possibly fewer side effects from GH overshoot or non-GH hormone activation

It is characterised not just by lysosomal enzyme deficiencies but also by the impact this has on inflammatory pathways

Patients with recurrent drug-induced priapism who require long-term antipsychotic therapy necessitate psychiatry and urology comanagement, with likely use of adjunctive medications (eg, gabapentin, baclofen, or pseudoephedrine)