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Remarkably, many of these profibrotic genes have a correlation coefficient equal to or greater than 0.90 with one another

Carvalho RD, Breyner N, Menezes-Garcia Z, Rodrigues NM, Lemos L, Maioli TU, et al

Future efforts should focus on developing responsive delivery systems (e.g., oxidative stress-sensitive controlled-release carriers, ultrasound-mediated reversible blood-brain barrier opening) to achieve non-invasive, lesion-specific targeting while minimizing off-target effects