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Despite the development of numerous drugs targeting specific pathological features of AD, such as amyloid-beta (A) deposition and neurofibrillary tangles, very few have been approved in the past 20 years, underscoring the limitations of single-target therapeutic approaches

CaminhaMCMoreiraABMatheusFCRiegerDKMoreiraJDDalmarcoEMet al

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This knowledge will provide new insights for basic research and clinical practice on PE with appropriate iron supplementation and tight lipid control, and may lead to novel therapeutic strategies

83 A recent study intriguingly identified that the lactylation of K124 on regulator of chromosome condensation 2 (RCC2), a chromosome condensation regulation-related protein, assists in the recruitment of free SERBP1, which further stabilizes MAD2L1 mRNA and promotes the proliferation of breast cancer cells