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Measurement of prothrombin fragment 1 + 2 by ELISA The presence of a hypercoagulation state was evaluated by measuring the level of prothrombin fragment 1 + 2 using a Human Prothrombin Fragment 1 + 2 (F1 + 2) ELISA Kit (MyBioSource, Inc., San Diego, CA, USA), according to the manufacturer protocol

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Baseline DEXA or InBody scan, baseline labs including fasting insulin and a comprehensive metabolic panel, body measurements, and progress photos

Additionally, there can be challenges in targeting the NPs specifically to melanoma cells while avoiding healthy tissue

SeVitE (milk replacer supplemented with 0.6 mg organic selenium/kg + 100 IU vitamin E, N = 14)