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Description

Much research has demonstrated the cytotoxic and neurotoxic effects of the medications used for general anesthesia (3)

The Asp 2 analog, which had not been evaluated in the earlier studies, also exhibited pronounced inhibitory activity

Acta Pharmacol Sin (2022) 43(8):1889904

doi: 10.3389/fphar.2023.1069348 202 BondiCDRushBMHartmanHLWangJAl-BatainehMMHugheyRPet al

The most recent clinical trial candidate showing promise is ursodeoxycholic acid (UDCA), a drug often used in chronic inflammatory liver disease with an extensive safety profile (Sathe et al., 2020)