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Those suffering from chronic disease - Persons with Crohns disease, Lou Gehrigs disease, diabetes, osteoporosis or muscular degeneration all tend to find improvement in their symptoms once they introduce B12 shots.

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doi: 10.1097/CCM.0b013e3181a98899 [DOI] [PubMed] [Google Scholar] 6

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However, some people, especially those with specific genetic mutations, might not absorb it as efficiently