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Antioxidant mechanism of polyphenol-rich nymphaea Nouchali leaf extract protecting DNA damage and attenuating oxidative stress-induced cell death via Nrf2-mediated heme-oxygenase-1 induction coupled with ERK/p38 signaling pathway

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Moreover, also HO-1, a downstream target of Nrf2, is also essential for antioxidative defense in melanocytes

In contrast, DFO treatment did not induce this increase: the proportions of parasites expressing the iron utilization-related genes among all parasites were 91.7% (3 h) and 87.2% (9 h), respectively

Proc Soc Exp Biol Med 223:5966 Pfeilschifter J, Kditz R, Pfohl M, Schatz H (2002) Changes in proinflammatory cytokine activity after menopause