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Emerging evidence suggests that microglia, as key neuroimmune modulators within the CNS, influence the incidence and progression of cardiovascular diseases, including hypertension, myocardial infarction, and ischemia/reperfusion injury, through mechanisms potentially linked to altered autonomic nervous system activity (Wang M

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We denatured, reduced, and renatured purified AP, generating an inactive, reduced enzyme that could regain activity through thiol oxidation