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Moreover, non-enzymatic reactions with ascorbate, pyruvate, -ketoglutarate, and oxaloacetate can lead to ROS depletion

doi: 10.1523/jneurosci.5956-09.2010 3 BellotG.Garcia-MedinaR.GounonP.ChicheJ.RouxD.PouyssgurJ.et al

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Central Sensitization in Fibromyalgia A key aspect of fibromyalgia's chronic pain is its association with central sensitizationa condition where the central nervous system goes into a persistent state of high reactivity, amplifying pain signals