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This confirmed that the binding of GSH did not hinder the ability of the VP1 hydrophobic pocket to accommodate capsid-binding drugs such as GPP3, so effects at the two druggable sites, separated by some 22 in the capsid are likely to be additive

doi: 10.1038/mto.2015.7

Several sequencing-based studies published in the last 2 years have found that the makeup and functions of the gut microbiota vary between patients with heart failure (HF) and healthy participants, with some consistent findings but significant variance between investigations ( Table 3 )

Li Y, Li M, Feng S, Xu Q, Zhang X, Xiong X, et al