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I've seen it happen to countless clients, and it's happened to me as well.

Low Vitamin B12 due to Drinking Too Much Alcohol Regular alcohol consumption has a number of health drawbacks, including impacting sleep, causing weight gain, affecting mood and there is also evidence it has nutritional disadvantages, too

Arterial blood gas revealing low pH (acidosis) and low bicarbonate

Concise review: gamma-glutamyl transferase - evolution from an indiscriminate liver test to a biomarker of cardiometabolic risk Metab Target Organ Damage 2022;2:17

Pyruvate dehydrogenase (PDH) promotes the transportation of pyruvate into mitochondria, where it is converted to acetyl-CoA [111,112,113,114]