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Disulfide-directed multicyclic peptide libraries for the discovery of peptide ligands and drugs

Science Press, Beijing, p 575 Zhao G, Zhao D, (2007) Chinese medicinal composition for treating chronic gastritis, gastric ulcer and digestive tract ulcer CN 101019999 Zhang AQ, Zhang JS, Tang QJ, Jia W, Yang Y, Liu YF, Fana JM, Panc YJ (2006) Structural elucidation of a novel fucogalactan that contains 3-O-methyl rhamnose isolated from the fruiting bodies of the fungus Hericium erinaceus

doi: 10.1111/j.1750-3639.2004.tb00049.x 117 HowellOWReevesCANicholasRCarassitiDRadotraBGentlemanSMet al

In other words, the peaks and valleys of metabolite and cofactor availability such as acetyl-CoA, NAD + /NADH, and -ketoglutarate (-KG) create a landscape of potential chemical modifications 13,15 (Fig

Further research is needed to refine these approaches and develop more precise treatments