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Critically, Porphyromonas gingivalis infection - a microbial driver shared by both oesophageal squamous cell carcinoma (ESCC) and OSCC [94] - promotes IFNGR1 palmitoylation, accelerating its lysosomal degradation and malignant progression in ESCC [95]

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Hee-June Yoo, National Institute of Agricultural Science, South Korea, for supporting the greenhouse experiments and heavy metal analysis

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Author Contributions AM wrote the manuscript, designed and carried out the rodent experiments and performed human fibroblast culture