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Overcoming these hurdles through engineering, surface modification, or standardized manufacturing protocols is essential for their clinical translation in lung cancer immunotherapy

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The high expression level of DPP1 and serine proteases in mast cells, neutrophils, and cytotoxic T lymphocytes suggests that curtailing the downstream effects of DPP1 activation may alter many cellular functions, including mast cell function, and impede diseases driven by mast cells