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Description

10LH CAR does not induce cell killing in SW620 HLA-A*24:02PHOX2B cells expressing at 5:1 effector-to-target ratio

Two compounds, PRT062607 and CYC116, were co-crystallized with TcPINK1 (PDB 8UCT and 8UDC, respectively)

Significantly, anti-angiogenic effects of paclitaxel have been linked with its cytostatic effects (G 2 -M arrest, increase in Bax/Bcl-2 ratio, and mitochondria permeabilization) that eventually result in apoptosis [126]