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Description

This paper developed a more specific small-molecule G6PD inhibitor and found a role for the oxPPP in T cell function

Despite their benefits, weight gain, diabetes, metabolic syndrome, and cardiovascular disease are common side effects of this type of drugs, and insulin resistance that may be induced because of their use has been related to changes in DNA methylation, particularly with hypomethylation in fatty acyl CoA reductase 2 [246]