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Normalised counts of organoid samples were filtered for the 51 ferroptosis-related genes (Supplementary Table 1) and a hierarchically clustered heatmap was generated depicting gene z-score

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The latter is characterized by centers that send orexigenic and anorexigenic signals regulating starvation and satiety, reducing and increasing energy expenditure, respectively

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With increasing methionine intake, the transsulfuration pathway, which provides a substrate for GSH synthesis, is increased