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Positive controls, including T3 (3,3,5-Triiodo- L-thyronine sodium salt, Sigma, T6397) at 30 nM and clemastine fumarate (Sigma, SML0445) at 500 nM were used as positive controls, with their respective vehicles (DMSO and PBS) as negative controls

CLSM images (Figure 7) revealed that 8-MOP encapsulated in dendrimers was able to penetrate into deep skin layers, epidermis and dermis, compared to standard formulation

This isnt always readily absorbed by everyone

The cuvettes contents are well mixed, and the absorbance is subsequently measured at a wavelength of 412 nm using a spectrophotometer

IDO and TDO inhibitors in cancer immunotherapy: Mechanisms, clinical development, and future directions