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Under this assumption, we propose a model (Figure 9)

The downstream pathway of Nrf2, on the other hand, involves inhibitory effects on oxidative stress, inflammation and apoptosis, including but not limited to several important protein molecules, such as HO-1, SOD, MDA, TNF-, ILs, the caspase family of proteins, Bcl-2 and Bax

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Yildirim C, Cevik S, Yamaner H et al (2022) Boric acid improves the behavioral, electrophysiological and histological parameters of cisplatin-induced peripheral neuropathy in rats

Additionally, frequent use of alcohol as a sleep aid leads to tolerance, with its sedative effects waning within about a week of repeated use