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d , Single-cell transcript counts of Abca1 in 1.2 10 4 FAK-KO and 1.5 10 4 FAK-WT cells experiencing increasing levels of local crowding (interquartile area in grey)

No DMSO, just 1cc EDTA in 500cc D5W, with 2CC B6 and 15cc ascorbic acid given intravenous over 3 hours

The block in bench-to-bedside translation may in part be due to a lack of pre-clinical HFpEF models that adequately recapitulate heterogeneity of the human condition