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Extending from the physical and biochemical properties of the engineered NPPC-derived exosomes, we further develop an injectable hydrogel filler based on clinically-tested ECM analogs including hyaluronic acid (HA) and oxidized chondroitin sulfate (OCS) as the exosome delivery platform (HACS@CPP-miR-Exo) for post-discectomy management, which is not only well tolerated in the operation-induced NP cavity but also enables sustainable release of the engineered exosomes to mediate continuous ferroptosis reversal in NPCs (Fig

AI to enable plant cell metabolic engineering

Correct measured deficiencies Protein and amino-acid adequacy Zinc, manganese, magnesium and selenium when deficient Vitamin D, B12 and other documented deficiencies Copper correction according to copper, zinc and ceruloplasmin 3

It occurs very rarely in cases of delayed healing and prolonged inflammation post laser resurfacing

tricolor Drought stress generated superoxide from photosynthetic and respiratory electron leakage in chloroplast