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All of them are homodimers integrated in membranes which have a transmembrane domain characterized by a thioredoxin fold

84,85,161163 When MLCK1 is recruited to PAMR, it generally phosphorylates the myosin light chain (MLC), resulting in contraction of the cytoskeleton and occludin internalization

Oxidative stress during viral infection: a review

(2019) Prevalence and associated risk factors of periodic limb movement in sleep in two German population-based studies

To determine the effects of stimulating TCA cycle activity, we treated hepatocytes with dichloroacetate (DCA), which stimulates substrate entry into the TCA cycle by inhibiting PDKs (Constantin-Teodosiu et al., 1999, Wu et al., 2018)