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The musculoskeletal syndrome of menopause

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On the other hand, inactivation of CDKN2A gene encoding the tumor suppressor p16INK4a might facilitate escape from senescence in these cells, explaining the association between p16INK4a loss and worse outcomes in PA patients ( Table 2 List of in vitro models developed for preclinical testing

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For example, Gao and colleagues demonstrated the antioxidant properties of hollow spherical selenium nanoparticles, suggesting their potential to mitigate systemic toxicity through targeted delivery (148)