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Description

It can include the back, arms and legs

SIRT2, present both in nuclear and cytoplasmic compartments, can increase MFN2 and decrease DRP1, thus promoting mitochondrial fusion 104,105

Meanwhile, Arbaclofen can correct the social deficits in mice while also normalizing excessive baseline protein synthesis, abnormal AMPA receptor internalization, and increased dendritic spine density (147, 148)