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doi: 10.3389/fimmu.2020.593103 126 ShahDMahajanNSahSNathSKPaudyalB

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Although early up-regulation of these enzymes are involved in the host antiviral response, an overproduction of nitric oxide could be detrimental to the CNS and lead to brain damage (Baraano and Snyder, 2008a)