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Clin Chim Acta 22(3):393397 Allain CC et al (1974) Enzymatic determination of total serum cholesterol

The active site forms at the interface of these domains, stabilized by key amino acid residues (81)

Excess reagents were removed by buffer exchange with 3 8 M urea (pH 7.0) resulting in a final volume of 3040 L

Concurrently, total brain ferritin levels are decreased despite elevated ferritin deposition in the substantia nigra, where an increased ferritin heavy chain-to-light chain ratio is associated with reduced iron storage stability (Friedman and Galazka-Friedman, 2012)