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Figure 2 4.1 Imaging of Gln metabolism predicts treatment response Abnormal Gln metabolism has facilitated the use of non-invasive imaging techniques for early tumor diagnosis and treatment monitoring, such as 18F-(2S,4R)-4-fluoroglutamine (18F-FGln) PET and L-(71)

Kolb D, Kolishetti N

It activates three hormone receptors involved in metabolic regulation : GLP-1 (glucagon-like peptide-1): reduces appetite and slows gastric emptying GIP (glucose-dependent insulinotropic polypeptide): supports insulin response and metabolic efficiency Glucagon: increases energy expenditure and promotes fat utilization Because of this three-pathway action, retatrutide is often described as a triple-agonist medication

Improves Overall Skin Texture: Regular use can result in smoother skin texture, reducing the appearance of pores and roughness