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Glutathione protects many thiol groups in molecules such as proteins and enzymes, so that the enzymes maintain their biological activities

Mediators Inflamm 2014;2014:837107

Excess of heme induces tissue factor-dependent activation of coagulation in mice

Multiple viruses, including influenza virus, syncytial virus (RSV), and SARS-CoV-2, can activate the PI3K/Akt pathway to inhibit the pro-apoptotic protein B-cell lymphoma 2 (Bcl-2)-associated agonist of cell death, enhance Bcl-2 expression, thereby delaying host cell apoptosis and extending the viral replication window (Zhao et al., 2014)

Together with pericytes, astrocytes are an essential component of the bloodbrain barrier (BBB), which selects and transports molecules from the bloodstream, and allows for the transfer of nutrients to neurons (Figure 1B)