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Clinical trials commonly start with 1 mg weekly and gradually increase the dose to higher levels such as 4 mg, 8 mg, or even 12 mg depending on the study protocol

In particular, the immediate recovery of collaterals and bypassing of the obstruction, a feature noted in the present study, and the rapid reestablishment of blood flow in both the ischemic and reperfusion conditions may be responsible for its subsequent strong angiogenic effect and its healing effects[2,22-28], which are more pronounced than those of standard anti-ulcer agents[23]

Methods of Bioavailability Assessment Blood concentration method This approach assesses a drug's pharmacokinetic effects on the body by monitoring the drug concentration in blood over time

A., & Morales-Gonzlez, J

10.1002/wrna.52 41