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This reduced excitability is likely mediated by a shunting mechanism, 16 whereby increased tonic GABA conductance lowers membrane resistance and dampens depolarization from excitatory inputs without altering EPSP amplitude

Birkeland, K

Unlike other GH-releasing peptides (e.g., GHRP-2 or GHRP-6), ipamorelin does not stimulate the release of ACTH or cortisol, nor does it alter other hormones (prolactin, FSH, LH, TSH), demonstrating high selectivity for inducing GH secretion only

For measuring ROS production, 5 10 4 Veros cells were plated in black/clear bottom 96 well Thermo (165305) plates overnight