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The inactivation of the DNA mismatch repair system by oxidative stress, in turn, may be responsible for the microsatellite instability that is implicated in the initiation and promotion of colitis-associated carcinogenesis [142]

Common mild observations in studies include transient facial flushing and headache

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People with a family history of chronic diseases : Individuals with a family history of chronic diseases such as heart disease or cancer might consider testing their glutathione levels, as low glutathione has been associated with an increased risk of these conditions