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In addition, two groups have shown that inhibition of protein geranylgeranylation leads to the disassembly of HCV replication complexes and strong inhibition of HCV RNA replication 69,70

Since the vertebrate SVCT4 is not a VC transporter, if true, it could be that there are no VC transporters in non-bilaterian and protostomian, species, or that the vertebrate SVCT4 lost its ancient VC transporter activity